What is PGD?
Preimplantation Genetic Diagnosis (PGD) is an advanced genetics test used with in vitro fertilization to determine the status of an embryo’s chromosomes. PGD prenatal diagnosis is performed on early embryos prior to implantation in the uterus and initiation of pregnancy.
PGD will help you conceive a healthy baby free of disease, and eliminate the chance of certain genetic conditions from being passed on to your child. PGD also can be used to select the gender of your child, useful for medical reasons or family balancing. Following the PGD analysis, only embryos that test normal are selected for transfer to the uterus on day 4 or 5 of egg retrieval.
EmBIO Director Dr. Thanos Paraschos is acclaimed for performing the first pre-implantation genetic diagnosis in the world in 1989, alongside IVF pioneers Lord Professor Robert Winston and Professor A.H. Handyside at Hammersmith Hospital in the UK.
Near 100% Success Rate
With an accuracy rate astonishingly reaching just under 100%, Dr. Paraschos has been performing IVF involving PGD and Pre-implantation genetic screening (PGS) since 1996. It is his most successful method of gender selection. His success rates are so high, because the test takes place before the IVF process is even initiated, allowing you to decide on the gender of the child if you wish to.
When the embryos grow to a certain size in our lab, our expert embryologists remove 1 or 2 Blastomeres from the embryo to determine if the embryo is different from the others. After about 24 hours, the possibility of chromosome abnormalities or genetic diseases will have been diagnosed, and only the selected embryos without abnormalities will be chosen for the IVF cycle.
A normal cell has 46 chromosomes in 23 pairs, half from each parent, which contain DNA -- our genetic roadmap. A baby carrying an extra or missing chromosome may be born with mental and/or physical defects, such as down syndrome. Chromosomal abnormality also can prevent the embryo from attaching to the wall of the uterus, eliminating any chance of pregnancy. It may cause the implanted embryo to stop developing, resulting in a pregnancy loss.
Why choose PGD?
PGD is a technique developed to give you even more control over your family planning. This process was designed, not just to give you preference for a male or female baby, but to help patients eliminate gender select illnesses, such as Daltonism, more commonly known as colour blindness. The embryo’s with these illnesses will be detected during PGD and removed from the IVF process to prevent the possibility of genetically passed down diseases.
The remaining embryos with normal test results which will not be used for the IVF treatment will be stored for you in our state of the art cryo-preservation facilities in case you decide to have another IVF cycle in the future.
If you require more information on the PGD technique that happens prior to the IVF cycle, please do not hesitate to get in touch with Dr. Thanos Paraschos here at EmBIO Medical Center. Fill out our contact form here and Dr. Paraschos will personally get back in touch with you within 24 hours.